Showing posts with label The role of inflammatory cytokines as key modulators of neurogenesis. Show all posts
Showing posts with label The role of inflammatory cytokines as key modulators of neurogenesis. Show all posts

Monday, January 12, 2015

TRENDS IN NEUROSCIENCES

feedamail.com TRENDS IN NEUROSCIENCES

The role of inflammatory cytokines as key modulators of neurogenesis
Neurogenesis is as a complex neurobiological process by which new neurons are generated from neural stem cells (NSCs) [1]. The ability of stem cells to self-renew and then differentiate into specific cell subtypes has been demonstrated both in vitro [2] and, more recently, in vivo [3]. For this reason, the term 'neural progenitor cells' (NPCs) is now used to loosely define all dividing cells with some ability to generate different neural units [3]. Current data have estimated that approximately 700 new neurons are added to the adult human hippocampus daily, suggesting that adult hippocampal neurogenesis has a critical role in mediating human brain functions, such as memory formation and cognition [4,5].
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