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Celladon says heart treatment fails in trial Celladon Corp said its heart failure gene therapy Mydicar failed to meet its primary and secondary endpoints in an important trial. "We are surprised and very disappointed that Mydicar failed to meet the endpoints in the CUPID2 trial, and we are rigorously analyzing the data in an attempt to better understand the observed outcome," Celladon's chief executive, Krisztina Zsebo, said in a statement on Sunday. According to the company, the gene therapy failed to show a significant treatment effect when compared to placebo. Read More »Decline in U.S. science spending threatens economy, security: MIT By Sharon Begley NEW YORK (Reuters) - Warning of an "innovation deficit," scientists at the Massachusetts Institute of Technology say declining government spending on basic research is holding back potentially life-saving advances in 15 fields, from robotics and fusion energy to Alzheimer's disease and agriculture. Science funding is "the lowest it has been since the Second World War as a fraction of the federal budget," said MIT physicist Marc Kastner, who led the committee that wrote "The Future Postponed" report, issued on Monday. Federal spending on research as a share of total government outlays has fallen from nearly 10 percent in 1968, during the space program, to 3 percent in 2015. Read More »Lice Shouldn't Keep Kids from School, Doctors Say Head lice are annoying, but they don't actually make people sick, and children with the condition should not be kept away from school, according to new guidelines from a leading group of pediatricians. The guidelines, from the American Academy of Pediatrics, say that although head lice can cause itching, they are not known to spread disease, and the insects are not very likely to spread from one child to another within a classroom. For this reason, "no healthy child should be excluded from school or allowed to miss school time because of head lice or nits," the guidelines say. In addition, screening kids at schools for head lice does not reduce the occurrence of the condition in classrooms over time, so routine screenings at schools should be discouraged, the AAP says. Read More »Air Pollution May Shrink the Brain, Study Suggests Breathing polluted air every day may change a person's brain in ways that end up leading to cognitive impairment, according to a new study. The investigators used magnetic resonance imaging (MRI) to look at the participants' brain structures, and compared the images with the air pollution levels in the places where the participants lived. The researchers found that an increase of 2 micrograms per cubic meter in fine-particle pollution — a range that can be observed across an average city — was linked to a 0.32 percent reduction in brain volume. That amount of change in brain volume "is equivalent to about one year of brain aging," said study author Elissa H. Wilker, a researcher in the cardiovascular epidemiology research unit at Beth Israel Deaconess Medical Center in Boston. Read More »Exercise Won't Fix the Obesity Epidemic, Researchers Argue The food industry has helped push the belief that people's sedentary lifestyles are solely to blame for widespread obesity, three researchers argue in a new editorial. And by doing so, the industry has deflected attention from the role that sugary drinks and junk food play in making people fat, said Dr. Aseem Malhotra and his colleagues. Malhotra is an honorary consultant cardiologist at Frimley Park Hospital in the United Kingdom and science director of the advocacy group Action on Sugar. "The public health messaging around diet and exercise, and their relationship to the epidemics of type 2 diabetes and obesity, has been corrupted by vested interests," the researchers write in their editorial, published today (April 22) in the British Journal of Sports Medicine. Read More »Scientist Hawking tells upset fans Malik may be in parallel One Direction Read More » Scientist Hawking tells upset fans Malik may be in parallel One Direction Read More » Big Butts Can Lie: Bootylicious Baboons May Not Be Most Fertile Read More » Man-Made Earthquakes Rising in US, New Maps Show Read More » Stargazer Enjoys Venus View from Giant's Causeway in Ireland (Photo) Read More » Having an 'Invisible' Body Could Reduce Social Anxiety Read More » Women Who Sit Too Much Have Higher Breast Cancer Risk Too much time spent sitting at work and during off hours may increase women's risk of breast and endometrial cancer, a new study from Sweden suggests. Researchers analyzed information from more than 29,000 Swedish women ages 25 to 64 who did not have cancer at the study's start. Study subjects were divided into three groups: those who had a sedentary job (such as working in an office) and did not participant in recreational sports, those who had a sedentary job but did participate in sports (such as running and handball), and those who had a physically active jobs that required more standing up (such as being a teacher) and also participated in recreational sports. Women who were not active at their work or in their leisure time were 2.4 times more likely to be diagnosed with endometrial cancer (a cancer of the uterus lining), and also 2.4 times more likely to be diagnosed with breast cancer before menopause, compared with those who were active at their jobs and in their leisure time. Read More »Prostate Cancer Risk Linked to Baldness Men who are losing their hair due to male pattern baldness may be at increased risk of dying from prostate cancer, a new study suggests. What's more, those with moderate balding were 83 percent more likely to die from prostate cancer, compared to those with no balding. The findings support the hypothesis that a shared biological process influences both balding and prostate cancer, the researchers said. Men with male pattern baldness have been found to have higher levels of male hormones, and these hormones also fuel the growth of prostate cancer cells. Read More »Study blames global warming for 75 percent of very hot days
Global warming to blame for most heat extremes - study Read More » Bizarre Cousin of T. Rex Was a Vegetarian Read More » Elephant Contraception? How a Vaccine is Replacing Sharpshooters (Op-Ed) Karen Lange is senior content creator at the Humane Society of the United States (HSUS). For 15 years, researcher Audrey Delsink has observed the elephants in South Africa's Greater Private Makalali Game Reserve. As she's watched them, recording the effects of a contraceptive vaccine called PZP, she's seen something that's beyond the scope of her research: evidence of awareness. Read More »Not Just a Band-Aid: How 'Smart Bandages' Will Change Medicine (Video) Read More » Songbirds Emerge for Spring, But Is the Timing Off? (Essay) Read More » Learning from Earth's Smallest Ecosystems (Kavli Hangout) Read More » From Crisis to Myth: The Packaging Waste Problem (Op-Ed) He is the editor of The Use Less Stuff Report, a highly respected and widely read newsletter aimed at spreading the benefits of source reduction. Twenty years ago, the late "garbologist" William Rathje of the University of Arizona and I penned an op-ed on enviro-myths, touching on topics from garbage to the health of the planet. Our point: To solve environmental problems, we all need to work with the facts, not feel-good sound bites and myth-perceptions. One particularly stubborn enviro-myth continues to persist: We're burying ourselves in a growing mountain of packaging waste. Read More »Climate Deniers to Pope Francis: 'There Is No Global Warming Crisis' Read More » Global warming to blame for most heat extremes - study By Alister Doyle OSLO (Reuters) - Global warming is to blame for most extreme hot days and almost a fifth of heavy downpours, according to a scientific study on Monday that gives new evidence of how rising man-made greenhouse gases are skewing the weather. "Already today 75 percent of the moderate hot extremes and about 18 percent of the moderate precipitation extremes occurring worldwide are attributable to warming," the climate scientists, at the Swiss university ETH Zurich, wrote. In Britain, for instance, that is 33.2 degrees Celsius (92 F) in south-east England or 27 degrees further north in Edinburgh, according to the UK Met Office Hadley Centre. The scientists, Erich Fischer and Reto Knutti, noted that a U.N. study last year found that it was at least 95 percent probable that most warming since the mid-20th century was man-made. Read More »Zebrafish 'inner ear' development wins science video prize By Ben Gruber Monday April 27, 2015 - This is a video of a lateral line, an organ that allows fish to sense water movement, developing in a zebra fish. Using an imaging technique called Selective Plane Illumination Microscopy, which uses sheets of lights to illuminate sub-cellular activity, Dr. Mariana Muzzopappa and Jim Swoger from the Institute for Research in Biomedicine in Barcelona Spain, claimed top honors in this year's Nikon Small World in Motion Photomicrography Competition. Second place went to Dr. Douglas Clark from San Francisco, California who used polarized light to create a time-lapse movie showing crystals forming on a single drop of a solution saturated with caffeine in water. Third place honors went to Dr. John Hart from the Department of Atmospheric and Oceanic Science at the University of Colorado-Boulder for a detailed look at oil floating on the surface of water. Read More »'Jigsaw puzzle' dinosaur Chilesaurus boasted weird mix of traits Read More » Citizen Scientists Discover Five New Supernovas Read More » Astronauts in Space Mourn Nepal Earthquake Victims Read More » | ||||
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Monday, April 27, 2015
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