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Cytoplasmic dynein heavy chain: the servant of many masters Giampietro Schiavo, Linda Greensmith, Majid Hafezparast, Elizabeth M.C. Fisher. • The cytoplasmic dynein complex is the main retrograde motor in all eukaryotic cells. • This complex is built around a dimer of cytoplasmic dynein heavy chains (DYNC.... Read More » Central regulation of body-fluid homeostasis Masaharu Noda, Hiraki Sakuta. • We review recent progress in the identification of brain sensors to monitor body-fluid conditions. • The Na-level sensor, Nax, is expressed in glial cell.... Read More » Rhodopsin homeostasis and retinal degeneration: lessons from the fly Bo Xiong, Hugo J. Bellen. • Rhodopsin are universal light sensors and are very abundant in photoreceptors. • Disruption of rhodopsin homeostasis causes retinal degeneration in flies and humans.... Read More » Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics Paul J. Lucassen, Eva F.G. Naninck, Johannes B. van Goudoever, Carlos Fitzsimons, Marian Joels, Aniko Korosi. Early-life stress lastingly affects adult cognition and increases vulnerability to psychopathology, but the underlying mechanisms remain elusive. In this Opinion article, we propose that early nut.... Read More »Towards a 'systems'-level understanding of the nervous system and its disorders Irfan A. Qureshi, Mark F. Mehler. • Unanticipated interconnections exist between the nervous system and the immune system, energy homeostasis, and the gut microbiome. • Crosstalk between these systems.... Read More » NMNATs, evolutionarily conserved neuronal maintenance factors Yousuf O. Ali, David Li-Kroeger, Hugo J. Bellen, R. Grace Zhai, Hui-Chen Lu. • Neurons require a 'maintenance plan' that enables them to endure daily wear and tear. • NMNATs function as NAD synthesizing enzymes and chaperones. • Loss of NM.... Read More » | ||||
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Saturday, November 2, 2013
FeedaMail: TRENDS IN NEUROSCIENCES
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