FeedaMail: TRENDS IN NEUROSCIENCES

	TRENDS IN NEUROSCIENCES
	Toward a cross-species understanding of empathy Jaak Panksepp, Jules B. Panksepp. • Signs of empathy have been observed in many mammals, including laboratory rodents. • 'Primal empathy' utilizes the seven basic emotional systems of the mammalian br.... Read More » Current insights into the C9orf72 repeat expansion diseases of the FTLD/ALS spectrum Marc Cruts, Ilse Gijselinck, Tim Van Langenhove, Julie van der Zee, Christine Van Broeckhoven. • C9orf72 repeat expansions are the most frequent cause of FTLD/ALS spectrum diseases. • Expanded C9orf72 repeats are associated with diverse neurologic.... Read More » Epigenetic layers and players underlying neurodevelopment Janine M. LaSalle, Weston T. Powell, Dag H. Yasui. • Epigenetic modifications are long-lived layers of past transcriptional events. • The relationship of DNA methylation to transcription depends on genomic context. Read More » Novel pathogenic pathways in diabetic neuropathy Jennifer Zenker, Dan Ziegler, Roman Chrast. • Glial cells play a critical role in maintenance of axonal integrity and function. • Diabetes mellitus modifies axon–glia interactions at nodal areas of PNS nerves.<.... Read More » Spikes and ribbon synapses in early vision Tom Baden, Thomas Euler, Matti Weckström, Leon Lagnado. • The retina of vertebrates and invertebrates encodes visual signals with both spikes and graded signals. • In vertebrates, 'digitization' of the visual signal begins.... Read More » Changing the tune: plasticity and adaptation of retrograde signals Karl J. Iremonger, Jaclyn I. Wamsteeker Cusulin, Jaideep S. Bains. • Retrograde signaling can be modified by a diverse array of intracellular signaling pathways. • Retrograde signals interact with other neurotransmitters to determine.... Read More » Emerging role for astroglial networks in information processing: from synapse to behavior Ulrike Pannasch, Nathalie Rouach. • Astrocytes are organized in extensive and plastic gap-junction mediated networks. • We evaluate their role in synaptic activity, neuronal circuit dynamics and behav.... Read More » Neurons and circuits for odor processing in the piriform cortex John M. Bekkers, Norimitsu Suzuki. • The piriform cortex (PC) is critical for olfactory processing in mammals. • The PC is increasingly studied as a model circuit for cortical sensory processing. •.... Read More » Metabolic signaling by lactate in the brain L. Felipe Barros. • Synaptic activity is accompanied by a transient rise in brain tissue lactate concentration. • The rise in lactate is explained by acute stimulation of glycolysis in.... Read More » Autophagy in axonal and dendritic degeneration Yi Yang, Michael Coleman, Lihui Zhang, Xiaoxiang Zheng, Zhenyu Yue. • Neuritic degeneration is a pathological feature of many neurodegenerative diseases. • Autophagy regulates protein and organelle homeostasis in axons and dendrites.<.... Read More » Steady or changing? Long-term monitoring of neuronal population activity Henry Lütcke, David J. Margolis, Fritjof Helmchen. • We review in vivo chronic extracellular recording and two-photon calcium-imaging studies that address the question of the stability of neuronal population activi.... Read More » Development of human embryonic stem cell therapies for age-related macular degeneration Amanda-Jayne F. Carr, Matthew J.K. Smart, Conor M. Ramsden, Michael B. Powner, Lyndon da Cruz, Peter J. Coffey. • Age-related macular degeneration (AMD) is the leading cause of vision loss in older adults. Recent research for treating AMD has focused on replacing the retinal pigmen.... Read More »
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